Hua Zhang Selected Research

Amyloid (Amyloid Fibrils)

1/2022	Targeting Amyloids with [18F]AV-45 for Medullary Thyroid Carcinoma Positron Emission Tomography/Computed Tomography Imaging: A Pilot Clinical Study.
6/2021	Apolipoprotein E ε4 and ε3 alleles associate with cerebrospinal fluid tau and cognition in the presence of amyloid-β in mild cognitive impairment but not in Alzheimer's disease.
1/2021	The Role of Apolipoprotein E ε4 in Early and Late Mild Cognitive Impairment.
1/2018	Targeting Alzheimer's Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment.
1/2018	Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer's disease.
10/2015	PPAR-α agonist regulates amyloid-β generation via inhibiting BACE-1 activity in human neuroblastoma SH-SY5Y cells transfected with APPswe gene.
9/2015	Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease.
3/2015	Hydrogen sulfide-induced processing of the amyloid precursor protein in SH-SY5Y human neuroblastoma cells involves the PI3-K/Akt signaling pathway.
2/2011	The molecular basis of distinct aggregation pathways of islet amyloid polypeptide.
6/2010	Role of presenilins in neuronal calcium homeostasis.

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Hua Zhang Research Topics

Disease

404	Neoplasms (Cancer) 05/2024 - 05/2002
91	Inflammation (Inflammations) 12/2024 - 10/2007
62	Neoplasm Metastasis (Metastasis) 02/2024 - 12/2002
62	Infections 01/2024 - 11/2006
54	Lung Neoplasms (Lung Cancer) 05/2024 - 10/2004
51	Breast Neoplasms (Breast Cancer) 02/2024 - 05/2004
37	Fibrosis (Cirrhosis) 12/2023 - 05/2009
33	Liver Cirrhosis (Hepatic Cirrhosis) 01/2024 - 11/2012
33	Carcinogenesis 03/2023 - 12/2005
31	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 02/2008
31	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 05/2009
31	Hypoxia (Hypoxemia) 01/2023 - 03/2002
25	Carcinoma (Carcinomatosis) 05/2024 - 12/2002
25	COVID-19 04/2024 - 01/2020
25	Allergic Rhinitis 02/2024 - 01/2009
24	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2024 - 02/2011
21	Hypertension (High Blood Pressure) 12/2023 - 06/2007
21	Wounds and Injuries (Trauma) 12/2023 - 01/2008
21	Body Weight (Weight, Body) 11/2023 - 09/2006
21	Nasopharyngeal Carcinoma 08/2022 - 10/2007
20	Pre-Eclampsia (Preeclampsia) 02/2024 - 03/2012
20	Glioma (Gliomas) 08/2023 - 05/2007
20	Adenocarcinoma of Lung 01/2023 - 02/2014
19	Pain (Aches) 03/2024 - 10/2007
19	Type 2 Diabetes Mellitus (MODY) 01/2023 - 09/2007
19	Ischemia 01/2023 - 08/2004
17	Gestational Diabetes (Gestational Diabetes Mellitus) 12/2024 - 03/2013
17	Cognitive Dysfunction 04/2024 - 01/2014
16	Epilepsy (Aura) 04/2024 - 09/2007
16	Atherosclerosis 03/2024 - 02/2003
16	Liver Diseases (Liver Disease) 03/2024 - 01/2012
16	Colorectal Neoplasms (Colorectal Cancer) 02/2024 - 08/2006
16	Insulin Resistance 11/2023 - 01/2007
15	Thrombosis (Thrombus) 04/2024 - 04/2009
15	Colitis 04/2024 - 06/2005
14	Non-alcoholic Fatty Liver Disease 04/2024 - 09/2008
14	Rheumatoid Arthritis 12/2023 - 01/2005
14	Cardiovascular Diseases (Cardiovascular Disease) 10/2023 - 04/2009
14	Stomach Neoplasms (Stomach Cancer) 03/2023 - 12/2002
14	Stroke (Strokes) 01/2023 - 06/2010
13	Virus Diseases (Viral Diseases) 04/2024 - 06/2013
13	Hemorrhage 04/2024 - 02/2008
13	Brain Neoplasms (Brain Tumor) 01/2024 - 05/2007
13	Leukemia 01/2020 - 02/2003
12	Hepatitis B 02/2023 - 01/2011
12	Pneumonia (Pneumonitis) 10/2022 - 11/2013
11	Autoimmune Diseases (Autoimmune Disease) 04/2024 - 08/2009
11	Osteosarcoma (Osteogenic Sarcoma) 10/2023 - 01/2013
11	Chronic Hepatitis B 01/2023 - 02/2006
11	Reperfusion Injury 12/2022 - 03/2002
11	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2020 - 04/2014

Drug/Important Bio-Agent (IBA)

154	Proteins (Proteins, Gene)FDA Link 12/2024 - 07/2003
90	Biomarkers (Surrogate Marker)IBA 05/2024 - 03/2009
45	CytokinesIBA 01/2024 - 03/2002
45	Peptides (Polypeptides)IBA 04/2023 - 02/2008
39	MicroRNAs (MicroRNA)IBA 06/2023 - 03/2009
31	Messenger RNA (mRNA)IBA 12/2024 - 12/2003
31	LipidsIBA 04/2024 - 05/2011
31	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 03/2013
24	RNA (Ribonucleic Acid)IBA 04/2024 - 09/2008
23	LigandsIBA 02/2023 - 05/2002
23	Liposomes (Liposome)IBA 10/2021 - 08/2005
22	Antiviral Agents (Antivirals)IBA 04/2023 - 01/2010
20	AntibodiesIBA 03/2024 - 04/2004
20	Therapeutic UsesIBA 12/2022 - 06/2005
20	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2022 - 04/2004
19	EnzymesIBA 04/2024 - 04/2004
19	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2023 - 03/2002
19	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 05/2002
18	Long Noncoding RNAIBA 02/2024 - 05/2013
16	AntioxidantsIBA 01/2023 - 06/2012
15	Interleukin-6 (Interleukin 6)IBA 07/2023 - 12/2003
15	Small Interfering RNA (siRNA)IBA 11/2021 - 01/2007
14	Anti-Bacterial Agents (Antibiotics)IBA 05/2024 - 01/2008
14	CollagenIBA 03/2024 - 11/2006
14	LipopolysaccharidesIBA 08/2023 - 01/2018
14	Immunoglobulin G (IgG)IBA 05/2023 - 09/2005
14	Polysaccharides (Glycans)IBA 07/2022 - 06/2005
14	AntigensIBA 11/2021 - 07/2003
13	HydrogelsIBA 04/2024 - 09/2015
13	AutoantibodiesIBA 03/2024 - 01/2005
13	Phosphotransferases (Kinase)IBA 03/2024 - 08/2004
13	Oxygen (Dioxygen)IBA 03/2023 - 03/2007
13	Cisplatin (Platino)FDA LinkGeneric 03/2023 - 08/2008
12	Paclitaxel (Taxol)FDA LinkGeneric 02/2024 - 01/2012
12	C-Reactive ProteinIBA 12/2023 - 01/2013
12	Immune Checkpoint InhibitorsIBA 10/2023 - 01/2018
12	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 03/2008
11	Carbon Tetrachloride (Tetrachloromethane)IBA 12/2023 - 01/2015
11	VaccinesIBA 12/2023 - 07/2005
11	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2023 - 08/2005
11	Interleukin-17 (Interleukin 17)IBA 01/2023 - 11/2012
11	Glycoproteins (Glycoprotein)IBA 07/2022 - 06/2013
11	Estrogens (Estrogen)FDA Link 01/2018 - 05/2004

Therapy/Procedure

189	Therapeutics 05/2024 - 12/2004
59	Drug Therapy (Chemotherapy) 03/2024 - 04/2004
46	Immunotherapy 02/2024 - 03/2011
31	Radiotherapy 01/2024 - 11/2007
20	Chinese Traditional Medicine (Traditional Chinese Medicine) 03/2024 - 05/2009
15	Lasers (Laser) 04/2023 - 09/2008